About Aspirin Mechanism of Action (LM-01)


                                    Aspirin Structure

Several thousands of tons of aspirin (acetylsalicilate) are consumed  each year all over the world for the relief of headaches, inflammed joint, pain in general and fever. Also, at low doses, in the prevention of heart attacks. The relief caused by aspirin in these conditions is based mainly in aspirin effects on eicosanoid metabolism. Aspirin binds covalently (and so act as an irreversible inhibitor) to this enzyme of eicosanoid metabolism:

a) Lipoxygenase

b) Thromboxane Synthase

c) Prostacycline Synthase

d) Prostaglandin Synthase

e) Phospholipase A2





Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s