Question (B-02), Bioenergetics: Arsenic poisoning and Enzymes of the Central Metabolic Pathway
Most forms of arsenic are toxic, but the arsenite form is much more toxic than others. Arsenite forms a stable complex with enzyme-bound lipoic acid. For the most part, arsenic poisoning is explained by inhibition of those enzymes that require lipoic acid as a coenzyme. So, two important enzymes inhibited as a consequence of arsenic poisoning are:
a) Citrate synthase and Pyruvate dehydrogenase
b) Citrate synthase and Isocitrate dehydrogenase
c) Citrate synthase and alpha-keto glutarate dehydrogenase
d) Isocitrate dehydrogenase and alpha-ketoglutarate dehydrogenase
e) Pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
f) Pyruvate dehydrogenase and isocitrate dehydrogenase
Can you find the metabolites of the Krebs Cycle in this puzzle?