Q: About a patient with a glucagonoma.

 

Mouse Islet of Langerhans immunostained for Glucagon

 

Assume that you find a patient with a glucagon-secreting pancreatic tumor (glucagonoma). Which one of the following is most likely to result from hyperglucagonemia?

 

a)     Decreased lipolysis

 

b)     Hyperglycemia

 

c)      Increased muscle protein synthesis.

 

d)     Increased liver glycolytic rate

 

e)     Increased glycogenesis

Biochemistry Question CM-21

 

A 13 year-old patient with Type I diabetes mellitus, home alone,  takes an insulin injection before lunch but then he gets concentrated in a videogame he is playing and does not eat. Approximately 3 hours later, he becomes sweat, shaky and confused. These symptoms have appeared as a consequence of:

 

a) increased glucagon release from the pancreas

 

b) decreased glucagon release from the pancreas

 

c) increased insulin  release from the pancreas

 

d) decreased insulin release from the pancreas

 

e) high sugar levels in blood

 

f) low sugar levels in blood

 

 

Q: About Congenital Adrenal Hyperplasia

Question about Hormones (H-07)

 

Congenital Adrenal Hyperplasia (CAH) occurs as a consequence of genetic deficit of enzymes that participate in the conversion of cholesterol to cortisol. Failure in producing cortisol results in an increase of ACTH secretion and consequently an increased production of androgens and aldosterone disbalance, (most of the cases also show an unability to synthesize aldosterone).  As a result, clinical consequences can be detected in the newborn, from ambiguous genitalia up to salt-losing crisis that threatens the life of the newborn. That is why newborn screening for this disease exists in almost all states. The enzyme deficiency that is most common in CAH is:

 

a)     11 hydroxylase

 

b)     17 hydroxylase

 

c)      21 hydroxylase

 

d)     Desmolase

 

e)     HMGCoA reductase

 

f)       HMGCoA synthase

 

g)     HMGCoA Lyase

 

h)    Sterol cyclase