Q: About GSD and Glycogen structure (C-09)

 

Andersen’s Disease is a rare disease caused by the deficit of the Branching enzyme, responsible for the formation of branches in glycogen structure. This results in an abnormal glycogen with few branching points and long peripheral chains. Clinically, hepatoesplenomegaly, cirrhosis of the liver and hepatic failure are major concerns. As the problem is located in the branching points, it is obvious that there is a defect in the formation of:

 

a)     Alpha 1,4 -O-glycosidic linkages

 

b)     Alpha 1,6 -O-glycosidic linkages

 

c)      Alpha 1 ,Beta 2 -O-glycosidic linkages

 

d)     Beta1,3 -O-glycosidic linkages

 

e)     Beta1,4 -O-glycosidic linkages

 

f)       Beta1,6 -O-glycosidic linkages

 

Carbohydrate Extended Matching Questions

 

  

Questions C-06 to C-08 

    

 

 

 

 

 

 

Another format you can expect to see in your Multiple Choice exams:

 

 

 

 

Choose, among the following polysaccharides, which correspond to each of the questions that appear below:

 

 

a)     Cellulose

 

 

b)     Glycogen

 

 

c)      Starch

 

 

d)     Hyaluronic acid

 

 

e)     Heparin

 

 

f)       Chondroitin Sulfate

 

 

(C-06) This carbohydrate acts as lubricant of synovial fluid and contributes to

            tensile strength and elasticity of cartilages and tendons. It is also an

            important component of skin.

 

Answer

 

 

(C-07) It is the most important polysaccharide in human diet:

 

Answer

 

 

(C-08 ) It is the form in which glucose is stored in muscle and liver for ulterior use as fuel:

 

Answer

 

 

More questions about Carbohydrates and Medicine

Question C-03

 

A 15-year-old black male patient complains that lately, after the ingestion of dairy products, he experiences bloating, cramps and flatulence, and sometimes diarrhea.  With this information, it is reasonable to think that the patient is intolerant to:

 

a)     cellobiose

b)     lactose

c)     mannose

d)     sucrose

e)     maltose

f)      isomaltose

g)     fructose

 

      Answer to C-03 

 

 

Question C-04

 

This heteropolysaccharide has multiple uses in Medicine that include its use in blood transfusions to prevent the blood from coagulating before administration, as anticoagulant therapy in prophylaxis and treatment of venous thrombosis and its extension, in pulmonary embolisms and in other similar situations:

 

a)     Hyaluronic acid

b)     Chondroitin- 4- Sulfate

c)     Chondroitin- 6- Sulfate

d)     Heparin

e)     Dermatan Sulfate

 

Answer to C-04

 

 

Question C-05

 

Human beings don’t have the enzymes necessary for the hydrolysis of the beta1,4-O-glycosidic linkages between molecules of glucose. That is why we can not digest this compound and it is part of some laxatives.

 

a)     cellulose

b)     glycogen

c)     amylose

d)     amylopectin

e)     lactose

f)       sucrose

  

 

 Answer to C-05