Q: About a patient with a glucagonoma.

 

Mouse Islet of Langerhans immunostained for Glucagon

 

Assume that you find a patient with a glucagon-secreting pancreatic tumor (glucagonoma). Which one of the following is most likely to result from hyperglucagonemia?

 

a)     Decreased lipolysis

 

b)     Hyperglycemia

 

c)      Increased muscle protein synthesis.

 

d)     Increased liver glycolytic rate

 

e)     Increased glycogenesis

Q: About Fructose 2,6 Bisphosphate (CM-24)

 

 

 

Which of the following sentences explain better the role of fructose  2,6-bisphosphate in glycolysis?

 

a) It antagonizes phosphofructokinase-1

 

b) It is an intermediate of glycolysis

 

c) It activates covalently  aldolase

 

d) It inhibits allosterically hexokinase

 

e) It allosterically activates phosphofructokinase-1

Q: About Glycogen Phosphorylase Regulation ( CM-23)

 

Allostery in Glycogen Phosphorylase

 

 

 Which of the following compounds is an allosteric activator of glycogen phosphorylase b  in muscle?

 

a)     AMP

 

b)     ATP

 

c)      Glucose

 

d)     Glucose 6 Phosphate

 

e)     GTP