Mouse Islet of Langerhans immunostained for Glucagon
Assume that you find a patient with a glucagon-secreting pancreatic tumor (glucagonoma). Which one of the following is most likely to result from hyperglucagonemia?
a) Decreased lipolysis
b) Hyperglycemia
c) Increased muscle protein synthesis.
d) Increased liver glycolytic rate
e) Increased glycogenesis
THE ISLETS OF LANGERHANS
http://isletbook.islets.se
The answer is hyperglycemia. Since glucagon catalysis glycogenolysis reaction which is the formation of glucose from glycogen in the liver and muscle cells. Hyperglucagonemia which is high level of glucagon in the blood will increase the rate at which glucose is being formed from glycogen and hence leading to high levels of glucose in the blood (hyperglycemia).